Showing posts with label Sugar. Show all posts
Showing posts with label Sugar. Show all posts

Wednesday, November 28, 2018

Diabetes UK’s tie-up with sugar giant

The Times  November 24 2018
The country’s leading charity for people with diabetes has been criticised over a £500,000 partnership with the soft drinks giant Britvic, which sells brands such as Tango and Pepsi.

Diabetes UK said it has agreed the three-year deal with the beverage producer despite the link between consuming too many sugary soft drinks and the life-threatening disease.

There are 3.8m people in England with type 2 diabetes, with about 200,000 new diagnoses every year. About 90 per cent of people with the disease are obese or overweight and consuming sugary drinks can increase the risk. The disease is associated with heart disease, amputation and blindness.

Monday, May 1, 2017

The food you eat directly affects your brain


iStock-92408982

Food is the best medicine. All your cells, bones, signaling molecules, and tissues are built from what you eat. For example, dietary fats are the building blocks of brain tissue and help balance hormones, and muscles are built from protein. Different vitamins and minerals are used to create energy and send electrical impulses along neurons so that we can move, think, and feel. A nourishing diet is the best strategy against depression.
The food we eat affects both our human and microbial cells. Numerous studies have shown that food changes the collection of trillions of beneficial bacteria in our guts, called the microbiome (1). In the name of convenience, flavor, or simply habit, so many of us consume inflammatory foods on a daily basis that increase intestinal permeability (leaky gut), harm the microbiome, and create chronic inflammation that can lead to depression.
Many studies have shown that people who eat an anti-inflammatory diet have significantly lower risks of depression (2-5). A recent study that tracked about 6,500 women over 12 years showed that women eating an anti-inflammatory diet had a 20% lower risk of developing depression than their peers (6). These anti-inflammatory diets consist of healthy fats, vitamins and antioxidants, and plenty of high-quality protein. On the other hand, many foods in the Standard American Diet (SAD) create chronic inflammation. These five inflammatory foods are the most frequent offenders I see when treating patients for depression:

Gluten

By now almost everyone has heard of gluten, the glue-like protein found in wheat. Grains like barley, rye, and contaminated oatmeal contain proteins that may be recognized by your body as gluten. Gluten and gluten-like proteins are some of the most inflammatory foods you can eat.
Many people think that gluten doesn’t affect them since they didn’t test positive for Celiac Disease. However, there are often false negatives on these tests because they don’t test for the full range of gluten proteins. Whether or not you have a diagnosed sensitivity to gluten, it isn’t doing you any favors, as it is almost exclusively present in processed foods.
Gluten drives inflammation by irritating the gut and gut microbes as well as intestinal tissues. This protein causes gut cells to produce a compound called zonulin, leading to intestinal permeability (or leaky gut). Gluten, which is a sticky protein, can also interfere with digestion by clumping together food particles. A recent study showed that gluten caused inflammation in gut cells of healthy volunteers, suggesting that gluten may cause adverse effects that can lead to depression in everyone (7).
Gluten consumption has been linked to depression, seizures, headaches, anxiety, nerve damage, and ADHD-like symptoms (8-10). Gluten has been linked to over 200 conditions, with neurotoxicity topping the list.
I’ve seen amazing recoveries from people who ditched the gluten – including myself. Gluten-free diets have helped people heal from too many seemingly hopeless diagnoses, like depression, to count!

Dairy

Believe me: I understand that dairy can be deeply pleasurable. Growing up in an Italian family, many of my fondest memories involve cheese, ice cream, ricotta, and yogurt. Science supports our attachment to dairy. On a molecular level, dairy contains morphine-like compounds which engage our opiate receptors and create mild dairy addiction (11).
A number of studies have shown that casein, a protein found in dairy products, can drive inflammation. Casein has been linked to several psychiatric conditions, ranging from schizophrenia to depression. Dairy may not be a problem for everyone, and some people can tolerate certain types of dairy, like raw milk. Fortunately, grassfed ghee is a wonderful substitute for butter.
If you’re suffering from symptoms of depression or anxiety, it’s worth eliminating dairy for 30 days and seeing how you feel. Some people are able to re-introduce dairy after a month off with no problems, while others totally lose their taste for it and even vomit when trying it again!

GMOs

Genetically-modified organisms (GMOs) have become a staple in the Standard American Diet. Beyond being a population-wide experiment in manipulating nature’s design, these foods, by definition, have been heavily treated with pesticides and herbicides. Since these chemicals have been designed to kill, it make sense that they’re quite toxic to our own human and microbial cells. Indeed, studies have shown that the common pesticide Roundup (glyphosate) causes cancer.
Alarmingly, these chemicals have been found in fetuses and breast milk, showing that the toxins used in modern farming are harming generations to come. Roundup is toxic to fetal cells and can lead to birth defects. This toxicant disrupts our microbiome, messing with the production of essential amino acids like tryptophan, absorption of minerals, and detoxification in the liver.
In addition to Roundup, the primary herbicide sprayed on GMOs like soy, GMOs also carry a variety of other toxicants that may be even more harmful in combination than alone. As even non-GMO foods can be contaminated with pesticides, I advise my clients, especially those suffering from depression, to eat organic.
Think eating organic is too expensive? Our Vital Mind Reset community support director, Shauna, has written an excellent article about eating healthy on food stamps!

Sugar and Artificial Sugar

Americans love sugar. The average American eats a staggering 164 pounds of sugar per year (12,13). Think about that for a moment. Even worse, sugar is highly addictive – the more we eat, the more we want.
Our bodies were not designed to handle the blood sugar and insulin roller coaster that many of us are on. Here’s how it goes: when you eat sugar, whether it’s in an obvious form like soda or a non-obvious form like pasta, your blood sugar increases quickly. This fast increase then spikes insulin. When insulin removes blood sugar, you then have a blood sugar crash, and cortisol comes in to compensate and try to move sugar out of storage and back into the bloodstream. This process, often called reactive hypoglycemia, is responsible for carb and sugar cravings (since your brain needs steady sugar to function), which leads to anxiety, headaches, irritability, and ultimately depression.
Overall, high blood sugar causes inflammation, which is one of the most significant risk factors for depression. Balancing blood sugar is one of the most effective treatments for depression and anxiety.
Sugar messes with our brain health in three main ways. First, sugar creates inflammation, often by spiking insulin and harming our gut microbiome. Next, sugar derails hormones, ultimately increasing levels of the stress hormone cortisol and disrupting the balance of sex hormones. Finally, sugar starves the brain and damages important structures in our bodies, like cell membranes and blood vessels (14). All this can lead to depression.
Because of all the research showing how harmful sugar is (15-18), food manufacturers have gotten creative with its naming. Don’t be fooled by code names like cane sugar, crystalline fructose, maltodextrin, high-fructose corn syrup – it’s all sugar.
It’s tempting to swap out sugar for artificial sweeteners. Artificial sugars, like aspartame and sucralose, are ‘zero calorie’ because they cannot be digested by the human body. But these chemicals don’t just pass through your body with no effect. Artificial sugars confuse hormones and change your microbiome. A high-profile scientific article showed that artificial sugar consumption leads to metabolic syndromes like insulin resistance and diabetes (19). Choose sweeteners that your body recognizes, like honey.

Vegetable Oils

The Standard American Diet contains large amounts of unhealthy fats, mostly in the form of commercial vegetable oils. Many processed foods, ranging from store-bought cookies to salad dressing, contain these oils. Vegetable oils include safflower oil, corn oil, sunflower oil, soybean oil, and canola oil. These oils are considered ‘processed’ because many high-heat and high-pressure steps, as well as chemical solvents, are required to create them. Further, many of these oils are made from GMOs.
For example, have you ever seen a canola plant? Canola oil, which has been touted as “heart healthy,” is derived from the Canadian rapeseed plant. Recognizing that “rape oil” was not a good marketing tactic, this invention was given a new name as a combination of “Canada” and “ola,” which means oil. Today, it is genetically modified by Monsanto to withstand saturation with Roundup herbicide (20, 21).
In short, our bodies do not recognize vegetable oils, especially when they’re heated and distorted. Consuming vegetable oils sounds the alarm of inflammation. Processed vegetable oils have been linked to thyroid dysfunction, cardiovascular diseases (22), nutrient deficiencies, cancer (23), and psychiatric disorders like depression (24, 25).

So what do I eat?!

I recommend that people give themselves 2-4 weeks to kick the sugar, gluten, and dairy habit. In this time, you can try non-GMO foods and healthier fats like olive oil and lard. People are amazed by how good they feel and how quickly their tastes change.
It’s can be overwhelming to try to overhauling your diet, and we’ve been led to seek quick and easy fixes. As someone who’s radically changed her diet and outlook on eating, I assure you that the deep commitment to yourself and your health is worth it. When you remove these inflammatory foods, you can more easily tap into your intuition to properly nourish yourself.

References
  1. http://stm.sciencemag.org/content/1/6/6ra14
  2. https://www.ncbi.nlm.nih.gov/pubmed/26344165
  3. https://www.ncbi.nlm.nih.gov/pubmed/27788314
  4. https://www.ncbi.nlm.nih.gov/pubmed/26586104
  5. https://www.ncbi.nlm.nih.gov/pubmed/27592562
  6. https://www.ncbi.nlm.nih.gov/pubmed/27498949
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1954879/
  8. http://jnnp.bmj.com/content/72/5/560.full
  9. https://www.ncbi.nlm.nih.gov/pubmed/19758171
  10. http://www.drperlmutter.com/about/grain-brain-by-david-perlmutter/
  11. https://www.ncbi.nlm.nih.gov/pubmed/26877644
  12. https://www.ncbi.nlm.nih.gov/pubmed/27327801
  1. https://www.ncbi.nlm.nih.gov/pubmed/27358413
  2. https://www.ncbi.nlm.nih.gov/pubmed/27312321
  3. https://www.ncbi.nlm.nih.gov/pubmed/27226903
  4. https://www.ncbi.nlm.nih.gov/pubmed/28035340
  5. https://www.ncbi.nlm.nih.gov/pubmed/28024276
  6. http://www.nature.com/nature/journal/v514/n7521/full/nature13793.html
  7. https://draxe.com/canola-oil-gm/
  8. http://onlinelibrary.wiley.com/doi/10.1002/047167849X.bio018/abstract
  9. https://www.ncbi.nlm.nih.gov/pubmed/24632108
  10. https://www.ncbi.nlm.nih.gov/pubmed/18584483
  11. https://www.ncbi.nlm.nih.gov/pubmed/26393778
  12. https://www.ncbi.nlm.nih.gov/pubmed/25499313 
Kelly Brogan MD

Thursday, February 4, 2016

The alarming link between energy drink consumption and young people suffering heart problems.

Monday, January 4, 2016

The high amounts of dietary sugar in the typical Western diet may increase the risk of breast cancer and metastasis to the lungs, according to a study at The University of Texas



The high amounts of dietary sugar in the typical Western diet may increase the risk of breast cancer and metastasis to the lungs, according to a study at The University of Texas MD Anderson Cancer Center.
The findings, published in the Jan. 1, 2016 online issue of Cancer Research, demonstrated dietary sugar's effect on an enzymatic signaling pathway known as 12-LOX (12-lipoxygenase).
"We found that sucrose intake in mice comparable to levels of Western diets led to increased tumor growth and metastasis, when compared to a non-sugar starch diet," said Peiying Yang, Ph.D., assistant professor of Palliative, Rehabilitation, and Integrative Medicine. "This was due, in part, to increased expression of 12-LOX and a related fatty acid called 12-HETE."
Previous epidemiological studies have shown that dietary sugar intake has an impact on breast cancer development, with inflammation thought to play a role.
"The current study investigated the impact of dietary sugar on mammary gland tumor development in multiple mouse models, along with mechanisms that may be involved," said co-author Lorenzo Cohen, Ph.D., professor of Palliative, Rehabilitation, and Integrative Medicine. "We determined that it was specifically fructose, in table sugar and high-fructose corn syrup, ubiquitous within our food system, which was responsible for facilitating lung metastasis and 12-HETE production in breast tumors."
Cohen added that the data suggested that dietary sugar induces 12-LOX signaling to increase risks for breast cancer development and metastasis.
Identifying risk factors for breast cancer is a public health priority, say the authors. The researchers state that moderate sugar consumption is critical, given that the per capita consumption of sugar in the U.S. has surged to over 100 lbs. per year and an increase in consumption of sugar-sweetened beverages has been identified as a significant contributor to an epidemic of obesity, heart disease and cancer worldwide.
"Prior research has examined the role of sugar, especially glucose, and energy-based metabolic pathways in cancer development," said Yang. "However, the inflammatory cascade may be an alternative route of studying sugar-driven carcinogenesis that warrants further study."
No previous studies have investigated the direct effect of sugar consumption on the development of breast cancer using breast cancer animal models or examined specific mechanisms, she added.
The MD Anderson team conducted four different studies in which mice were randomized to different diet groups and fed one of four diets. At six months of age, 30 percent of mice on a starch-control diet had measurable tumors, whereas 50 to 58 percent of the mice on sucrose-enriched diets had developed mammary tumors. The study also showed that numbers of lung metastases were significantly higher in mice on a sucrose- or a fructose-enriched diet, versus mice on a starch-control diet.
"This study suggests that dietary sucrose or fructose induced 12-LOX and 12-HETE production in breast tumor cells in vivo," said Cohen. "This indicates a possible signaling pathway responsible for sugar-promoted tumor growth in mice. How dietary sucrose and fructose induces 12-HETE and whether it has a direct or indirect effect remains in question."
The study team believes that the mechanism by which dietary sucrose or fructose affects breast tumor growth and metastasis, especially through the 12-LOX pathways, warrants further investigation.
MD Anderson research team members included Yan Jiang, Yong Pan, Patrea Rhea, and Lin Tan, all of Palliative, Rehabilitation and Integrative Medicine; Mihai Gagea, D.V.M., Ph.D., Veterinary Medicine & Surgery; and Susan Fischer, Epigenetics & Molecular Carcinogenesis.
The study was funded by the National Institutes of Health (P30CA0166672), Mr. and Mrs. H. Leighton Steward and EOG Resources, Inc.

Story Source:
The above post is reprinted from materials provided by University of Texas M. D. Anderson Cancer Center. Note: Materials may be edited for content and length.

Journal Reference:
  1. Yan Jiang, Yong Pan, Patrea R. Rhea, Lin Tan, Mihai Gagea, Lorenzo Cohen, Susan M. Fischer, and Peiying Yang. A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway. Cancer Res, January 1, 2016 76:24-29 DOI: 10.1158/0008-5472.CAN-14-3432

Tuesday, November 3, 2015

Why Sugar Is Called “The White Death”


Why-sugar-called-whiteDeath
As good as it may taste, sugar is NOT your friend. It may “feel” like your friend when it comforts you (due to the beta-endorphin rush in your brain), but sugar is really your ENEMY. Truth be told, regular consumption of sugary foods is one of the worst things that you can do for your health. Modern scientific research has shown us, beyond a shadow of a doubt, that sugar in your food (in all its myriad forms) is taking a devastating toll on your health.
Take a look at the sugar consumption trends over the past 300 years:
  • In 1700, the average person consumed about 4 pounds of sugar per year.
  • In 1800, the average person consumed about 18 pounds of sugar per year.
  • In 1900, individual consumption had risen to 90 pounds of sugar per year.
  • In 2012, more than 50% of all Americans consume 1/2 pound of sugar per day — translating to a whopping 180 pounds of sugar per year!
In 1890, only 3 people out of 100,000 had diabetes. In 2012, almost 8,000 out of every 100,000 people was diagnosed with diabetes!
The “sugar rush” has been targeted at our children. American children are consuming about 10 times as much sugar as they were in 1900, especially in the form of high fructose corn syrup (HFCS), which is the average American’s greatest source of calories! Highly addictive HFCS contains fructose and glucose, but they are NOT bound together (as they are in table sugar) so the body doesn’t need to break it down. Therefore, the fructose is absorbed immediately, going straight to the liver, which turns it into fat (VLDL and triglycerides).
According to Dr. Joseph Mercola:
“Fructose also tricks the body into gaining weight by fooling your metabolism (it turns off the appetite-control system). Fructose does not appropriately stimulate insulin, which in turn does not suppress ghrelin (the “hunger hormone”) and doesn’t stimulate leptin (the “satiety hormone”), which together result in your eating more and developing insulin resistance.” This process also suppresses the immune system.
But just because you avoid HFCS doesn’t mean that you’re in the clear. Excess intake of ALL processed sugars results in compromised immune function (decreasing the white blood cells’ ability to destroy bacteria), obesity, and diabetes.
And if that’s not enough, keep in mind that sugar is HIGHLY addictive! That’s right! Dr. Serge Ahmed of Bordeaux, France, has been working with rats and giving them the choice between cocaine and sugar. Guess which one wins, time and again?
That’s right … sugar!
It turns out that the sweet taste of sugar is more rewarding than the high of cocaine.
You see, sugar produces dopamine – a happy, feel-good chemical –  in the brain. People get addicted to eating sugar, whereby they need it to feel “normal” and they undergo “withdrawal” if they cut sugar from their diets. If they go “cold turkey” for a few days, their brain will begin to produce dopamine on its own, but the discomfort of the withdrawal process keeps many “sugar addicts” trapped in their addiction.
What is The Sugar Cancer Connection?
Due to the anaerobic respiratory mechanism exhibited by ALL cancer cell, sugar is cancer’s favorite food! And since half of the white sugar in the USA comes from sugar beets, you should remember that most beets are now genetically modified.  This is another reason to stay away from the “White Death” isn’t it?
I personally recommend that you avoid white sugar, brown sugar, agave, and all artificial sweeteners such as aspartame/AminoSweet, sucralose, and saccharin. If you have a sweet tooth, it’s best to stick with 100% pure stevia, xylitol, raw honey, pure maple syrup, molasses, and coconut sugar. The bottom line: if you want to be and stay healthy, you MUST take control of your sugar intake so that it doesn’t take control over you.
Ending the Sugar Confusion
It is easy to become confused by the various sugars and sweeteners, so here is a basic overview:
  • Saccharide = sugar
  • Glucose (aka “dextrose” or “grape sugar”), galactose (“milk sugar”), and fructose (“fruit sugar”) are all “monosaccharides” (i.e. single sugar molecules), known as “simple sugars.” The primary difference between them is the way your body metabolizes them.
  • Glucose is the form of energy you were designed to run on. Every cell in your body uses glucose for energy.
  • High amounts of fructose are very damaging to the body if it isn’t burned immediately for energy because it travels directly to the liver where it’s converted to triglycerides (fats). Excess triglycerides increase insulin resistance (and insulin production), thus contributing to diabetes in a “back door” fashion.
  • The simple sugars can combine to form more complex sugars, like sucrose (“table sugar”) which is a “disaccharide” comprised of 50% glucose and 50% fructose.
  • “Refined” white sugar (pure sucrose) is washed with a syrup solution, then with hot water, clarified (usually chemically) to remove impurities, decolorized, concentrated, evaporated, re-boiled until crystals form, centrifuged again to separate, then dried. By this point, any remnants of “natural goodness” and “nutritional value” have completely disappeared! Quite frankly, white sugar should be considered an “industrial product” rather than “food.”
  • “Brown sugar” is white sugar mixed with molasses.
  • “Raw” sugar is not really raw—it has been cooked, and most of the minerals and vitamins are gone. But it’s probably a little better than refined white sugar because it has a little of the molasses remaining.
  • Aspartame or AminoSweet is a neurotoxic rat poison … need I say more?
  • Splenda (sucralose) is NOT a sugar, despite its deceptive marketing slogan, “made from sugar.” It’s a chlorinated artificial sweetener in line with aspartame, though not quite as harmful.
  • Honey is approximately 50% fructose, but in natural (raw and unpasteurized) form contains many health benefits. Buying honey that is local and unpasteurized is best.
  • Stevia is an extremely sweet herb derived from the leaf of the South American stevia plant, which is completely safe (in its natural form.) Green stevia is the whole plant, while white stevia is processed and can often contain other ingredients like natural flavors or dextrose – a form of sugar. 100% green stevia in its natural state is what you want.
  • Agave nectar is made from the agave plant, which is a cactus. Sounds natural, right? Like maple syrup from a tree, or honey from a beehive. Only it isn’t. Agave is HIGHLY processed while the end product does not even remotely resemble the original agave plant. Furthermore, agave is approximately 80% fructose (much higher than honey and maple syrup).
  • HFCS – high fructose corn syrup –  is 55% fructose and 45% glucose. It is mostly genetically modified. Stay away!
  • Rapadura is the pure juice extracted from the sugar cane (using a press), which is then evaporated over low heat, whilst being stirred with paddles, then sieve ground to produce a grainy sugar. It has not been cooked at high heats or spun to change it into crystals, and the molasses is maintained in the sugar. “Sucanat” is the USA trade name for Rapadura.
  • Coconut sugar is made from the sweet watery sap that drips from the cut flower buds of the coconut palm. It has a low glycemic index (GI) and is rich in amino acids. It is typically less than 10% fructose, with sucrose being the primary component.
  • Xylitol is a sweetener known as a “sugar alcohol” (or polyol). Sugar alcohols are neither sugars nor alcohols – they are carbohydrates (with structures that happen to resemble sugar and alcohol). Xylitol is extracted from birch cellulose. Unlike sugar, Xylitol is slowly absorbed, does not cause a rapid blood sugar increase, and does not require an immediate insulin response from the body to be metabolized.  Moreover,  many studies have shown that it actually helps prevent dental cavities, ear infections and some evidence suggests that it helps prevent gum disease because Xylitol is an anti-bacterial.
Source

Friday, October 30, 2015

Reducing consumption of added sugar improves health in children

Tuesday, October 27, 2015

girl with sugared donut
Credit: iStock

Reducing consumption of added sugar, even without reducing calories or losing weight, has the power to reverse a cluster of chronic metabolic diseases, including high cholesterol and blood pressure, in children in as little as 10 days, according to a study by researchers at UC San Francisco and Touro University California.

“This study definitively shows that sugar is metabolically harmful not because of its calories or its effects on weight; rather sugar is metabolically harmful because it’s sugar,” said lead author Robert Lustig, M.D., MSL, pediatric endocrinologist at UCSF Benioff Children’s Hospital San Francisco. “This internally controlled intervention study is a solid indication that sugar contributes to metabolic syndrome, and is the strongest evidence to date that the negative effects of sugar are not because of calories or obesity.”
Jean-Marc Schwarz, Ph.D., of the College of Osteopathic Medicine at Touro University California and senior author of the paper, added, “I have never seen results as striking or significant in our human studies; after only nine days of fructose restriction, the results are dramatic and consistent from subject to subject. These findings support the idea that it is essential for parents to evaluate sugar intake and to be mindful of the health effects of what their children are consuming.”
The paper will appear online today (Oct. 27) and in the February 2016 issue of the Journal Obesity.

Restricting sugar intake

Metabolic syndrome is a cluster of conditions — increased blood pressure, high blood glucose level, excess body fat around the waist, and abnormal cholesterol levels — that occur together and increase risk of heart disease, stroke and diabetes. Other diseases associated with metabolic syndrome, such as non-alcoholic fatty liver disease and type 2 diabetes, now occur in children — disorders previously unknown in the pediatric population.
Participants were identified through the Weight Assessment for Teen and Child Health Clinic (WATCH) at UCSF Benioff Children’s Hospital San Francisco, an interdisciplinary obesity clinic dedicated to targeting metabolic dysfunction rather than weight loss. Recruitment was limited to Latino and African-American youth because of their higher risk for certain conditions associated with metabolic syndrome, such as high blood pressure and type 2 diabetes.
In the study, 43 children between the ages of 9 and 18 who were obese and had at least one other chronic metabolic disorder, such as hypertension, high triglyceride levels or a marker of fatty liver, were given nine days of food, including all snacks and beverages, that restricted sugar but substituted starch to maintain the same fat, protein, carbohydrate, and calorie levels as their previously reported home diets. Baseline fasting blood levels, blood pressure, and glucose tolerance were assessed before the new menu plan was adopted. The study menu restricted added sugar (while allowing fruit), but substituted it by adding other carbohydrates such as bagels, cereal and pasta so that the children still consumed the same number of calories from carbohydrate as before, but total dietary sugar was reduced from 28 to 10 percent, and fructose from 12 to 4 percent of total calories, respectively. The food choices were designed to be “kid food” – turkey hot dogs, potato chips, and pizza all purchased at local supermarkets, instead of high sugar cereals, pastries, and sweetened yogurt.
Children were given a scale and told to weigh themselves everyday, with the goal of weight stability, not weight loss. When weight loss did occur (a decrease of an average of 1 percent over the 10-day period but without change in body fat), they were given more of the low-sugar foods.
“When we took the sugar out, the kids started responding to their satiety cues,” said Schwarz. “They told us it felt like so much more food, even though they were consuming the same number of calories as before, just with significantly less sugar. Some said we were overwhelming them with food.”

Reducing harmful metabolic effects of obesity

After just nine days on the sugar-restricted diet, virtually every aspect of the participants’ metabolic health improved, without change in weight. Diastolic blood pressure decreased by 5mm, triglycerides by 33 points, LDL-cholesterol (known as the “bad” cholesterol) by 10 points, and liver function tests improved. Fasting blood glucose went down by 5 points, and insulin levels were cut by one-third.
“All of the surrogate measures of metabolic health got better, just by substituting starch for sugar in their processed food — all without changing calories or weight or exercise,” said Lustig. “This study demonstrates that ‘a calorie is not a calorie.’ Where those calories come from determines where in the body they go. Sugar calories are the worst, because they turn to fat in the liver, driving insulin resistance, and driving risk for diabetes, heart, and liver disease. This has enormous implications for the food industry, chronic disease, and health care costs.”
Other authors of the study include Susan Noworolski, Ph.D., Viva Tai, RD, MPH, Michael Wen, MS and Ayca Erkin-Cakmak, M.D., MPH of UCSF, Alejandro Gugliucci, M.D., Ph.D. of Touro University and Kathleen Mulligan, Ph.D., of UCSF and Touro University.
Funding was provided by the National Institutes of Health (NIH), UCSF Clinical Translational Science Institute (CTSI) and Touro University. None of the authors report any conflicts of interest.

University of California 

Tuesday, October 27, 2015

Study Links Sugar to Conditions That Lead to Diabetes, Heart Disease in Children Reducing sugar ‘reversed virtually every aspect’ of metabolic syndrome in children studied, says lead author Robert Lustig, who cites fructose as a culprit in the obesity epidemic

Reducing sugar ‘reversed virtually every aspect’ of metabolic syndrome in children studied, says lead author Robert Lustig, who cites fructose as a culprit in the obesity epidemic
Researchers offered new evidence Tuesday linking sugar consumption with conditions that can lead to diabetes and heart disease in children, fueling the debate over the causes of health problems related to obesity.
The study was designed to isolate the effect of added sugar in particular, as opposed to calories. Researchers from the University of California, San Francisco, and Touro University California took soda, pastries, sugary cereals and other foods and beverages sweetened with added sugar away from 43 Latino and African-American children and teens for nine days. They replaced those foods with pizza, baked potato chips, and other starchy processed foods.

Kids with food allergies won't be left out this Halloween. "Switch Witches" author Audrey Kinsman joins Lunch Break and discusses the Teal Pumpkin project, which encourages parents to hand out non-food treats on Halloween. Photo: NOBL Communications
The children were patients at a UCSF obesity clinic who had symptoms of metabolic syndrome, a cluster of conditions such as high cholesterol that can lead to diabetes. The change reduced sugar in their diets to 10% of overall calories from 28%, the researchers said.
Despite the short period of time and a diet still heavy on processed food, the researchers said they found striking results. The children’s cholesterol and other lipid levels improved, and their insulin levels dropped.
“We reversed virtually every aspect of their metabolic syndrome,” said Robert Lustig, a pediatric endocrinologist at UCSF Benioff Children’s Hospital San Francisco and lead author of the paper, published Tuesday in the journal Obesity. Of note, he said, triglycerides, high levels of which can contribute to a hardening of the artery walls and cause acute pancreatitis, showed a “very, very large improvement.”

The results are in keeping with Dr. Lustig’s long-held belief that sugar—specifically fructose, one of its components—stands out as a culprit in the obesity epidemic. Added sugar causes metabolic problems in the liver, interfering with the normal mechanisms that keep people from overeating, he says.
His provocative views have led him to clash with food and beverage makers, who argue that obesity is the result of excess calories overall and too little exercise, and that sugar should not be singled out.
The American Beverage Association, which represents beverage companies including Coca-Cola Co. and PepsiCo Inc., said the study didn’t demonstrate causation. “That’s the problem with studies like this. They raise an alarm without the proof,’’ said William Dermody, the association’s vice president of policy. “There’s nothing unique’’ about sugars or the calories in sugary products, he added.
Leon Bruner, chief science officer for the Grocery Manufacturers Association, said, “The broad conclusions and policy recommendations in this study only serve to further the author’s policy agenda without a sufficient scientific foundation.”
Some other researchers who study the effects of sugar on health praised the study. But they said more research is needed. The study didn’t have a control group of children, noted David Ludwig, director of the New Balance Foundation Obesity Prevention Center at Boston Children’s Hospital. “Because of the study’s design, we can’t be completely certain that the changes are fully attributable to changes in sugar intake,” said Dr. Ludwig. “It’s possible that other aspects of the diet or lifestyle changed.”
Still, he called the study “an interesting and useful step forward in assessing the effects of added sugar in children.”
Health authorities in the U.S. and elsewhere increasingly are targeting sugar. The World Health Organization recommended in March that adults and children cut sugar to less than 10% of their daily caloric intake. In July the Food and Drug Administration proposed that U.S. nutrition labels list added sugar amounts and a recommended maximum daily sugar intake of 200 calories—40 fewer calories than a 20-ounce Coca-Cola. Voters in Berkeley, Calif., in November approved a sugary drink tax, becoming the first U.S. city to pass such a measure.
Consumers also are backing away. In a nine-country survey this summer by Euromonitor International, 41% of respondents said they looked for limited or no added sugar on food labels. In the U.S., 71% said they were concerned about the amount of sugar they consumed, according to a March survey by the International Food Information Council. U.S. soda consumption has declined for 10 straight years.
WSJ